Men and women with thighs over 60cm (23.6in) in circumference have a lower risk of heart disease and early death, a study of 3,000 people suggests.
The relationship remains even when body fat, smoking and blood cholesterol are taken into account, a Danish team says.
Those with narrow thighs may not have enough muscle mass to deal with insulin properly, raising the risk of diabetes and, in turn, heart disease, they say.
Experts cautioned that the research needed corroborating.
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